This is possible but it's a bit involved. The reason is because the controller for the play page searches for the given video by ID. Video ID is guaranteed to be unique across your site. Video slug isn't. If you changed this to look up the video by the slug then it'll break when any two or more videos have the same title or slug.
If the above isn't a concern you then simply modify the query in the play page controller. Also modify the htaccess to send only the video slug to the play page.
I don't thing that will be a problem, I don't think that it will have duplicate titles however, I can mess with the video_add to don't let me upload a video if there's already one with the same title
thank you so much, it's working!! (I also needed to change one line at lib/Video.php)